CLINICAL INDICATION

• Intellectual disability/ developmental delay

• Multiple congenital anomalies/ dysmorphism

• Autism/autistic spectrum disorders

TESTING

Microarray Testing

LABORATORY REQUISITION REQUIRED

• IWK Clinical Genomics Postnatal Microarray Requisition

  • Instructions for Postnatal Microarray Requisition

• Signed Consent Form (page 2 of requisition)

SAMPLE REQUIREMENTS

5 ml peripheral blood in EDTA (purple top) tube

(2 ml peripheral blood (EDTA) from newborn < 1 mo.)

All specimens must be sent with a completed requisition. Specimen and requisition must both be labelled with the following matching identifiers:

• Patient's full name (first and last)
  AND

• Patient's Health Card Number or Hospital Identification Number

Any specimens received without the appropriate requisition or identifiers may be rejected.

TURN AROUND TIME

6 weeks routine

If urgent – contact laboratory

FOLLOW-UP TO ABNORMAL MICROARRAY

(as indicated on Microarray report)

• Targeted microarray analysis, MLPA, or other targeted molecular testing:

  • 3-5 ml peripheral blood (EDTA) from both biological parents

  • See Molecular testing

• Chromosome Analysis

  • 3-5 ml peripheral blood (sodium heparin) from both biological parents
    AND

  • 2 ml peripheral blood (sodium heparin) from proband

  • See Cytogenetic Testing

Direct all samples to Clinical Genomics Laboratory, IWK Health Centre
5850/5980 University Ave, PO Box 9700, Halifax, NS, B3K 6R8
For more information, email (preferred): clinicalgenomics@iwk.nshealth.ca or call 902-470-6504.